Anti-spermatogenic Effect of Hydro-ethanol Extract of Caesalpinia pulcherrima Leaves in Albino Rats
Pampa Lohar, Tanusree Mondal, Dibya Pal, and Debidas Ghosh
In this work investigates the anti-spermatogenic potential of the hydro-ethanol extract of Cae salpinia pulcherrima leaves (HEECPL) in male albino rats. Two groups of adult rats were created: the control group and the group that received HEECPL treatment (20 mg/100 g of body weight, orally once daily for 28 days). After completion of treatment, sperm count, motility, viability, and acrosome cap status were decreased significantly (p < 0.05), along with a decrease in acrosome cap status compared to the control. These results imply that HEECPL impairs spermatogenesis and sperm function, possibly through phytoconstituent mediated action of the extract. The study supports the possibility for the development of male contraceptive agent from C. pulcherrima as a natural and plant based effective birth control measure covering male which is not consider for this purpose like female.